Journal article
At-risk studies and clinical antecedents of psychosis, bipolar disorder and depression: A scoping review in the context of clinical staging
JA Hartmann, B Nelson, A Ratheesh, D Treen, PD McGorry
Psychological Medicine | CAMBRIDGE UNIV PRESS | Published : 2019
Abstract
Identifying young people at risk of developing serious mental illness and identifying predictors of onset of illness has been a focus of psychiatric prediction research, particularly in the field of psychosis. Work in this area has facilitated the adoption of the clinical staging model of early clinical phenotypes, ranging from at-risk mental states to chronic and severe mental illness. It has been a topic of debate if these staging models should be conceptualised as disorder-specific or transdiagnostic. In order to inform this debate and facilitate cross-diagnostic discourse, the present scoping review provides a broad overview of the body of literature of (a) longitudinal at-risk approache..
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Awarded by National Health and Medical Research Council
Funding Acknowledgements
J.A.H. was supported by a Netherlands Organization for Scientific Research (NWO)-Rubicon Grant (825.15.015). P.D.M. was supported by a Senior Principal Research Fellowship from the NHMRC (ID: 1060996) and B.N. was supported by a University of Melbourne Faculty Fellowship. P.D.M. reported receiving grant funding from the National Alliance for Research on Schizophrenia and Depression and unrestricted research funding from AstraZeneca, Eli Lilly, Janssen-Cilag, Pfizer and Novartis, as well as honoraria for educational activities with AstraZeneca, Eli Lilly, Janssen-Cilag, Pfizer, Bristol-Myers Squibb, Roche and the Lundbeck Institute.